Arteether is one of the artemisnin derivatives, which has proved to be efficient against acute severe falciparum malaria and can clear the parasite even in multiple drug resistant falciparum. However water insoluble nature of arteether limits the delivery of drug only by oral and i.m. parenteral route. This review highlights the properties of nanoparticles used in targeted drug delivery of arteether. Nanoparticles exploit biological pathways to achieve payload delivery to various cellular and intracellular targets. Different nanodispersion systems such as micelles, nanoemulsions and nanosuspensions along with advantages and disadvantages are discussed here. Various nano formulations represent promising means for delivering many bioactive agents, including peptide and protein drugs. The importance of these methods grew with the advancement in the understanding pharmacology of hydrophobic drugs as well as the ability to mass-produce these compounds.
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